I'm going to be moderating a panel this year at PyCon between 5 of the Python ORMs(Django, SQLAlchemy, SQLObject, Google App Engine, and web2py). To make my job easier, and to make sure the most interesting questions are asked I've setup a Google Moderator page for the panel here. Go ahead and submit your questions, and moderate others to try to ensure we get the best questions possible, even if you can't make it to PyCon(there will be a recording made I believe). I'll be adding my own questions shortly to make sure they are as interesting as I think they are.
Also, if you aren't already, do try to make it out to PyCon, there's still time and the talks look to be really exceptional.